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The Hidden Truth About Stress

Why it can kill you ... and how Magnolia Extract can alleviate its effects almost immediately!

Feeling stressed lately? Take charge of your stress!

If you're like most of us, you have too much on your plate and are under constant pressure—at work, home and maybe even at play. When is the last time you were able to really relax without any disturbances? Modern communications via e-mail, pagers and mobile phones have made it increasingly difficult to escape for even a few hours of undisturbed peace and quiet.

The problem is that instead of dealing with periodic episodes of stress, many of us are dealing with stress on a daily basis. And when stress becomes chronic, it is much more than an inconvenience. Every day, one million Americans are absent from work because of stress-related disorders. Most experts agree that stress is a major factor in disorders and diseases such as anxiety, insomnia, depression, ulcers, rheumatoid arthritis, headache, hypoglycemia, asthma, herpes, hypertension and heart disease. It's no wonder, then, that new research suggests that chronic stress speeds up the aging process of cells.

Where does stress come from?

Arguing with family, friends or co-workers, not getting enough sleep, worrying, working too hard or even playing too hard can all create stress. Weekend warriors, who try to make up for a week of inactivity by spending too many hours doing strenuous physical sports, raise their stress to unhealthy levels. Any activity that is practiced without moderation can lead to a stress response. Even positive experiences like a new job, marriage or moving into a new house can be a stress-provoking event—because stress is defined as a reaction to any stimulus that upsets our normal functioning.

Although it's impossible to live a stress-free life—simply because stress is a fact of life—we have good news for you! Now it’s easier than ever to neutralize stress before it takes its toll with Magnolia Extract—an ancient Chinese herb.

Magnolia Extract is the only natural and safe remedy in the world that relieves stress, anxiety and depression

There are lots of great herbs that have been proven to reduce stress, among other things. But nothing compares to Magnolia Extract when it comes to lowering stress response, anxiety and depression—almost immediately! And the best thing is that Magnolia Extract comes in a perfect form from nature … and doesn't produce any side effects.

How does it work?

Magnolia Extract is rich in the phytochemicals honokiol and magnolol, which have numerous health benefits. One of the most impressive benefits is their ability to alleviate stress while producing a calming effect. Dozens of animal studies have shown that they act as a non-addictive, non-sedating anxiolytic (anti-anxiety and anti-stress) agent at low doses.

That means a small dose of Magnolia Extract can help calm your nerves and alleviate anxiety, without making you sleepy. The beauty about these two phytochemicals is that honokiol exerts an anti-anxiety effect, and magnolol exerts an antidepressant effect.

Honokiol relieves stress without side effects

Honokiol has a long history of use in traditional Chinese formulas that relieve anxiety without leaving you feeling like you've been drugged. In a recent study to determine whether honokiol depresses the central nervous system in the same way as diazepam (commonly known as Valium), two groups of mice were treated with honokiol and diazepam before running through a maze. The honokiol group was more relaxed, and finished without any change in motor activity or muscle tone. On the other hand, the diazepam group exhibited several side effects, including sleepiness, disrupted learning and memory, muscle relaxation, and withdrawal symptoms. The results suggest that honokiol is less likely than diazepam to induce physical dependence, central nervous system depression, and amnesia when given at doses that produce an anti-anxiety effect.

A similar test found that honokiol significantly prolonged the time the animals spent in a maze, suggesting an anti-anxiety effect. Normally, when rodents are placed in a maze, they like to hide rather than explore because they get anxious. These rodents appeared to be more relaxed, and expressed curiosity about their environment. When the animals were given honokiol in various doses over a period of seven days, the effects remained the same: there was no change in motor activity or in the animals' performance. The animals receiving the diazepam (Valium), however, became dependent on the same dose, which hindered their performance.

Although no studies have specifically been done to show that Magnolia Extract reduces cortisol levels, it stands to reason that since so much impressive research has shown that it relieves stress, anxiety and depression, that Magnolia must also reduce cortisol—a by-product of stress.

More research is needed on the benefits of Magnolia and, in particular, we think research should be done to look at how Magnolia affects cortisol levels.

So far, what we do know is that when compared to pharmaceutical drugs such as Valium (diazepam), honokiol appears to be just as effective in its anti-anxiety activity, but without the strong sedative effect. This makes it an amazingly safe and effective remedy to help relieve the damaging effects of stress, without the tranquilizing side effects of drugs.

Powerful antioxidant protection

Honokiol and magnolol are both strong antioxidants, and it appears they can help protect cardiovascular health. Taiwanese researchers found that Magnolia Extract is 1,000 times more potent than alpha tocopherol (Vitamin E) in inhibiting lipid peroxidation, a major contributor to atherosclerosis and heart disease.

How safe is Magnolia?

No significant toxicity or adverse effects have been reported to date when it is taken as directed. Amazingly small doses (30 mg) of magnolol and honokiol are effective for anxiety and depression. Large doses exceeding 200 mg may cause a sedative effect and can interact with alcohol, increasing its effects; therefore, driving or operating dangerous equipment should be avoided when taking larger doses of Magnolia Extract.

Why take Magnolia Extract?

If you, or someone you care about, tend to suffer from stress, anxiety, or depression, Magnolia Extract may be just the thing you need to "take the edge off" and improve your quality of life … without the risk of side effects. If you are looking for a potent, natural and safe Anti-stress, anti-anxiety, antidepressant, or a daily supply of a powerful antioxidant, consider adding Magnolia Extract to your health regimen. Plant a tree, stop and smell the flowers … and gain a new appreciation for the Magnolia tree.

How much should you take?

For immediate relief take Magnolia Extract in 200 mg capsules. Up to 600 mg can be used occasionally for extra relaxation. For daily use, however, take 1-2 200 mg capsules.

Experience the difference!

While most typical Magnolia Extracts contain only 2% active ingredients, The Magnolia Extract found in TotalCalm contains 80% active ingredients, composed of almost equal amounts of honokiol and magnolol–so you will feel the effects almost immediately!

© Canopus BioPharma 2008
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